PE-22-28 — Research Peptide Overview, Specifications, and Sourcing
PE-22-28 is a synthetic peptide derived from the spadin analog of sortilin. It acts as a TREK-1 potassium channel blocker with rapid-onset antidepressant effects. Research focuses on neurogenesis stimulation in the hippocampus and treatment-resistant depression.
PE-22-28 is a synthetic peptide derived from the spadin analog of sortilin (NTSR3). It acts as a TREK-1 potassium channel blocker, mimicking the antidepressant mechanism of spadin with improved pharmacological properties. Research focuses on its rapid-onset antidepressant effects, neurogenesis stimulation in the hippocampus, and potential in treatment-resistant depression.
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